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  3. Medical: Pharmaceuticals

substituição em sensibilidade relativa à referência

11:52 Jan 19, 2024
Portuguese to English translations [PRO]
Medical - Medical: Pharmaceuticals / Prezista/ritonavir HIV drug
Portuguese term or phrase: substituição em sensibilidade relativa à referência
I am translating a booklet of information for healthcare professional relating to Prezista, a drug to treat HIV. This sentence is causing me problems in terms of the question posted above. "O fenótipo na linha de base de darunavir (substituição em sensibilidade relativa à referência) mostrou ser um fator preditivo de resultado virológico".
Heather Phillips
United Kingdom
Local time: 17:20


Summary of answers provided
5 +1shift in susceptibility relative to reference
philgoddard
3reference-associated sensitivity substitution
Ligia Fonseca


  

Answers


40 mins   confidence: Answerer confidence 3/5Answerer confidence 3/5
reference-associated sensitivity substitution


Explanation:
It would be good to have more examples of where "referência" appears in the text - is the substitution associated to the reference or is the sensitivity related to the reference?

Ligia Fonseca
United Kingdom
Local time: 17:20
Specializes in field
Native speaker of: Native in PortuguesePortuguese
Notes to answerer
Asker: Sorry, no other instances of reference in the document. Also, I am not sure if sensibilidade means sensitivity (to the drug) or susceptibility, although I suppose they are the same thing, so it doesn't really matter in this case.

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3 hrs   confidence: Answerer confidence 5/5 peer agreement (net): +1
shift in susceptibility relative to reference


Explanation:
You appear to be doing a back translation, so you just have to find the English product information. I don't know if your customer allows you to do this, but it does give you a definitive answer.

Baseline darunavir phenotype (shift in susceptibility relative to reference) was shown to be a predictive factor of virologic outcome.
http://www.google.com/url?q=https://ec.europa.eu/health/docu...




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Note added at 3 hrs (2024-01-19 15:37:48 GMT)
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Susceptibility means whether the virus is affected by the drug.

philgoddard
United States
Native speaker of: English
PRO pts in category: 2
Notes to answerer
Asker: Naughty of them not to have told me it is a back-translation, but that would explain the rather suspect Portuguese :) I found some good reference material and have added a note and writtenthe correct English in a couple of places already.


Peer comments on this answer (and responses from the answerer)
agree  Clauwolf
21 hrs
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