Glossary entry

German term or phrase:

Reifestörungen [kindlichen]

English translation:

maturation disorders [in children]

Added to glossary by Carolyn Korzilius
Jun 2, 2005 22:33
18 yrs ago
2 viewers *
German term

Reifestörungen [kindlichen]

Homework / test German to English Medical Medical: Pharmaceuticals hormones
gonadorelin a synthetic hormone for treating infertility in adults and kindlichen Reifestörungen
Change log

Jun 3, 2005 02:28: @caduceus (X) changed "Field (specific)" from "Biology (-tech,-chem,micro-)" to "Medical: Pharmaceuticals"

Proposed translations

+1
5 hrs
German term (edited): Reifest�rungen [kindlichen]
Selected

maturation disorders [in children]

IMO gonadorelin is the key for this translation issue, and so I tried first to find out, which uses are there for gonadotropin releasing hormone analogs especially in children.

See this text:
http://www.aetna.com/cpb/data/CPBA0501.html

You find that Reifungsstörungen - maturation disorders are sexual or pubertal disorders not meaning "retardation" of the process, but rather precocious puberty which is treated in children - together with infertiliy, also to be found in the table.

So I think maturation disorder is the correct term here, and the GH deficiency solution is an interpretation going too far, and maybe into the wrong direction.

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Note added at 6 hrs 1 min (2005-06-03 04:34:28 GMT)
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Here another text on uses of this drug category - also mentioning delayed puberty (!)

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Note added at 6 hrs 1 min (2005-06-03 04:34:43 GMT)
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forgot the link: http://www.drugs.com/MMX/Gonadorelin_Acetate.html
Peer comment(s):

agree Meturgan : legacy.uwcm.ac.uk/study/medicine/child_health/ research/endocrinology/clinical_services.htm - 27k
34 mins
thank you, it's exactly in your link: "gonadal and pubertal maturation disorders"!
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4 KudoZ points awarded for this answer. Comment: "This seems to fit the context best and the links back it up. thank you"
+1
4 mins
German term (edited): Reifest�rungen [kindlichen]

development disturbances (in children)

no my area but this might be ok ... not too sure about the "kindlich" here

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Note added at 5 mins (2005-06-02 22:39:15 GMT)
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or maybe: children with developmental disturbances
Peer comment(s):

agree Simon Hase (X) : I might also say "maturity", but I saw it in connection with children and adults
1 hr
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+3
12 mins
German term (edited): kindliche Reifest�rungen

children with growth hormone deficiency (GHD)

*

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Note added at 18 mins (2005-06-02 22:51:32 GMT)
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or growth hormone receptor deficiency (GHRD)

Gonadorelin ( goe-nad-oh-RELL-in) is a medicine that is the same as gonadotropin-releasing hormone (GnRH) that is naturally released from the hypothalamus gland.

http://en.wikipedia.org/wiki/Hypothalamus
http://www.becomehealthynow.com/article/bodynervousadvanced/...

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Note added at 24 mins (2005-06-02 22:57:59 GMT)
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...The hypothalamus is a substructure of the diencephalon and acts
as one of the most significant control centers of the brain. It
is located inferior to the thalamus, encapsulates the ventral
portion of the third ventricle, and lies just superior to the
pituitary gland, which it has direct regulatory control over
(Gunderson, 1996). Neurosecretory neurons in the hypothalamus
secrete releasing and inhibiting hormones which are carried to
the anterior pituitary where they exert their effects via
hypothalamic-hypophyseal portal veins. Included in the many
functions of the hypothalamus are regulation of food and water
intake, autonomic function, emotions, body temperature, motor
functions, and circadian sleep-wake cycles (Kalat, 2004).
Hormones secreted by the hypothalamus include Thyrotropin-
releasing hormone, Gonadotropin-releasing hormone, Growth-
releasing hormone...
http://www.humboldt.edu/~morgan/hyle_s05.htm

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Note added at 35 mins (2005-06-02 23:08:27 GMT)
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Growth hormone deficiency (GHD) is a developmental abnormality and it occurs in children who have a deficient pituitary gland that secrets inadequate amount of growth hormone.

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Note added at 16 hrs 43 mins (2005-06-03 15:17:17 GMT)
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I strongly believe that \'maturation disorder\' would not be the best term to use here, since there are a few very different maturation disorders, and this term is too broad. Gonadorelin is a drug used to cause ovulation in women and for treating growth hormone deficiency in teenagers. I don\'t think it should be implied that this drug may be used for treating any other maturation disorders in children. IMO, I don\'t see why using the terminology \'children with growth hormone deficiency\' would be going too far, if indeed this is exactly part of what this drug is used for.
Peer comment(s):

agree Simon Hase (X) : but I also saw "reifestoerung" in connection with adult female egg cell [ova] production
1 hr
Reifestörung is a developmental abnormality and is used in a few different contexts, however gonadorelin in context with children is used for growth hormone deficiency.
agree Johanna Timm, PhD : sounds most plausible given the context of hormone deficiencies
1 hr
Danke, Johanna
agree Sonia Soros
1 day 16 hrs
Thanks
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1 day 49 mins
German term (edited): Reifest�rungen [kindlichen]

developmental disorders

Disability Info: Pervasive Developmental Disorders (FS20)NICHCY briefing paper, discussing how Pervasive Developmental Disorder Not Otherwise Specified (PDD-NOS) fits into the category of Pervasive Developmental ...
www.nichcy.org/pubs/factshe/fs20txt.htm

Pervasive Developmental Disorders Information Page: National ...Pervasive Developmental Disorders (PDD) information sheet compiled by NINDS, the National Institute of Neurological Disorders and Stroke.
www.ninds.nih.gov/disorders/pdd/pdd.htm


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Note added at 1 day 56 mins (2005-06-03 23:29:30 GMT)
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Use of leuprolide acetate response patterns in the early diagnosis ...
... for possible pubertal developmental disorders and in 9 prepubertal controls [group
C; ... Gonadorelin/diagnostic use* Human Leuprolide/diagnostic use* ...
www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve& db=PubMed&list_uids=7507123&dopt=Abstract
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