Glossary entry

German term or phrase:

interferierend

English translation:

interfering

Added to glossary by Hannah Gunasingh
Jun 1, 2007 12:56
16 yrs ago
1 viewer *
German term

interferierend

German to English Medical Genetics Gentherapie / Gentransfer
)Weitere Sequenzen, die gentherapeutisch transferiert werden koennen, sind katalytische RNA, Ribozume und kurze interferierende RNA [RNAi]

2)Hier werden kleine doppelsträngige RNA-Oligonukleotide gebildet, die mit Ziel-messenger-RNA interferieren koennen.
[Medical]

[Need the English term for "interferierend" here. Thanks!!]
Proposed translations (English)
4 +3 interfering
3 +5 interfering
Votes to reclassify question as PRO/non-PRO:

Non-PRO (1): Stephen Sadie

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Proposed translations

+3
6 mins
Selected

interfering

small interfering RNA (siRNA), sometimes known as short interfering RNA or silencing RNA
Peer comment(s):

agree Cetacea : Thanks Cilian! I decided to hide my answer since two identical (cloned?) answers are enough... :-)
2 mins
agree Richard Benham
49 mins
agree Ingeborg Gowans (X)
4 hrs
Something went wrong...
4 KudoZ points awarded for this answer. Comment: "Thank you!"
+5
5 mins

interfering

That's a straightforward take-over from the English, as is often the case in scientific texts.

See example:

http://www.sciencedaily.com/releases/2005/07/050716163714.ht...
"First discovered only a few brief years ago, microRNAs are small, remarkably powerful molecules that appear to play a pivotal role in gene silencing, one of the body's main strategies for regulating its genome. A scant 22 nucleotides in length, miRNAs appear to work by binding to and somehow ***interfering*** with messenger RNA, itself responsible for translating genes into proteins."

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Note added at 6 mins (2007-06-01 13:03:40 GMT)
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Another one:

http://www.frost.com/prod/servlet/market-insight-top.pag?doc...
"RNA Interference
The gene-silencing horizon has significantly brightened recently by an emerging new technology called RNA interference (RNAi). RNAi is now the most talked about technology for target validation and therapeutics. RNAi technology involves targeting and ***interfering with messenger RNA (mRNA)***, a blueprint for building the protein being expressed. In this way, if a protein is involved in the progression of a disease, RNAi can be used to put a stop from it being expressed."
Peer comment(s):

agree Cilian O'Tuama : //years later- though your "nice references" (thanks steven) are verbs, not adjectives - not to worry :-)
1 min
True - I was looking at Hannah's second example when searching for sources :-)
agree Stephen Sadie : nice references and a touch quicker than cilian
3 mins
agree Cetacea
4 mins
agree rainerc (X)
7 mins
agree Richard Benham
51 mins
Something went wrong...
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