Glossary entry (derived from question below)
English term or phrase:
antisense oligomer conjugates
Serbian translation:
antisens oligomerni konjugati
Added to glossary by
Svetomir Mijovic
Aug 6, 2022 12:19
1 yr ago
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English term
antisense oligomer conjugates
English to Serbian
Medical
Medical: Pharmaceuticals
oligomer conjugates
The antisense oligomers are typically directed against RNA, either the sense strand (e.g., mRNA), or minus-strand in the case of some viral RNA targets. To achieve a desired effect of specific gene down-regulation, the oligomers generally either promote the decay of the targeted mRNA, block translation of the mRNA or block the function of cis-acting RNA elements, thereby effectively preventing either de novo synthesis of the target protein or replication of the viral RNA.
Proposed translations
(Serbian)
3 | antisens oligomerni konjugati | Nebojša Mihaljević |
Proposed translations
56 mins
Selected
antisens oligomerni konjugati
Reference:
1. U situacijama u kojima su i lek sa malim molekulom i odgovarajući oligomerni konjugat leka sa malim molekulom bioraspoloživi, poželjno je da konjugat poseduje oralnu bioraspoloživost koja iznosi najmanje 10% od oralne bioraspoloživosti leka sa malim molekulom u nekonjugovanoj formi (https://webcache.googleusercontent.com/search?q=cache:RL2LoQ...
2. ANTISENS OLIGOMERI I KONJUGATI KOJI
CILJNO DELUJU NA PCSK9 (https://www.zis.gov.rs/wp-content/uploads/Glasnik_03_2020.pd...
1. U situacijama u kojima su i lek sa malim molekulom i odgovarajući oligomerni konjugat leka sa malim molekulom bioraspoloživi, poželjno je da konjugat poseduje oralnu bioraspoloživost koja iznosi najmanje 10% od oralne bioraspoloživosti leka sa malim molekulom u nekonjugovanoj formi (https://webcache.googleusercontent.com/search?q=cache:RL2LoQ...
2. ANTISENS OLIGOMERI I KONJUGATI KOJI
CILJNO DELUJU NA PCSK9 (https://www.zis.gov.rs/wp-content/uploads/Glasnik_03_2020.pd...
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