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  3. Medical: Pharmaceuticals

shape of the product substrate curve

Russian translation: форма кинетической кривой для субстрата

GLOSSARY ENTRY (DERIVED FROM QUESTION BELOW)
English term or phrase:shape of the product substrate curve
Russian translation:форма кинетической кривой для субстрата
Entered by: Julia Berezina

07:54 Apr 9, 2021
English to Russian translations [PRO]
Medical - Medical: Pharmaceuticals / Pharmacology Written Summ
English term or phrase: shape of the product substrate curve
Previous study [see above, Flower 1973] showed that benzydamine inhibited the formation of PGF2« and PGD2 but it potentiated the synthesis of PGE2 by approximately 150%.
All these experiments were performed in the presence of 1 mM substrate, concentration chosen since it gave an almost equal production of PGE and PGF and smaller amounts of PGD.
However, when the reaction was performed under optimal conditions for PGE formation (0.5 mM substrate) no potentiation was observed.
The IC50 for PGE formation was about 5 mM.
The shape of the product substrate curve for PGE suggests strong substrate or product inhibition and the action of benzydamine could be the prevention of this situation, thus permitting an increase in the amount of PGE formed.
Julia Berezina
Local time: 00:55
форма кинетической кривой для субстрата
Explanation:
См. https://chem21.info/info/100281/
Selected response from:

Kseniia Abramenko
United Kingdom
Local time: 22:55
Grading comment
4 KudoZ points were awarded for this answer



Summary of answers provided
3форма кинетической кривой для субстрата
Kseniia Abramenko


  

Answers


2 hrs   confidence: Answerer confidence 3/5Answerer confidence 3/5
форма кинетической кривой для субстрата


Explanation:
См. https://chem21.info/info/100281/

Kseniia Abramenko
United Kingdom
Local time: 22:55
Specializes in field
Native speaker of: Russian
PRO pts in category: 8
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