English to Russian Medical Medical: Pharmaceuticals Non-clinical overview

Indapamide, however, is up to 500 times less potent than nifedipine and this may be why indapamide does not cause the acute side effects of the calcium vasodilators, such as orthostatic hypotension, flushing and increased heart rate, but has a more gradual action on reduction of blood pressure without acutely disrupting physiologic control systems.

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