Oct 27, 2021 00:54
2 yrs ago
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English term
inflammasome
GBK
English to Greek
Medical
Medical (general)
Definition from
Oxford English Dictionary:
A complex of proteins in the cytoplasm that regulates the activation of enzymes involved in immune and inflammatory responses to pathogens.
Example sentences:
Appropriate inflammasome activation is vital for the host to cope with foreign pathogens or tissue damage, while aberrant inflammasome activation can cause uncontrolled tissue responses that may contribute to various diseases, including autoinflammatory disorders, cardiometabolic diseases, cancer and neurodegenerative diseases. (Nature Portfolio)
The adaptor protein ASC must become linearly ubiquitinated and phosphorylated for inflammasome assembly to occur. After priming, canonical NLRP3 inflammasome activation requires a second, distinct signal to activate NLRP3 and lead to the formation of the NLRP3 inflammasome complex. (National Center for Biotechnology Info)
Potassium ion efflux (a common inflammasome activator) is an essential factor for the assembly and up-regulation of NLRP3 complexes induced by the agonist adenosine triphosphate (ATP). (Molecular Cancer)
Change log
Oct 22, 2021 11:50: changed "Kudoz queue" from "In queue" to "Public"
Oct 27, 2021 00:54: changed "Stage" from "Preparation" to "Submission"
Oct 30, 2021 01:56: changed "Stage" from "Submission" to "Selection"
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