Glossary entry

English term or phrase:

caprylate robustness experiment

Turkish translation:

kaprilat sağlamlık testi

Added to glossary by Can Saday
Oct 25, 2023 12:51
7 mos ago
12 viewers *
English term

caprylate robustness experiment

English to Turkish Medical Medical (general)
Arkadaşlar merhaba, virolojiyle ilgili metinde geçen ilgili terimi nasıl çevirebiliriz?

The additional caprylate robustness experiments were conducted as described previously except that 20 mL instead of 40 mL of Filtrate I was spiked to 10% with BVDV.
The additional caprylate robustness experiments were performed in duplicate.
References
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Change log

Nov 5, 2023 10:01: Can Saday Created KOG entry

Proposed translations

1 day 15 hrs
Selected

kaprilat sağlamlık testi

"Robustness" bir yöntemin bazı parametre değişikliklerinde geçerliliğini sürdürme düzeyini ifade eder. Burada madde olarak kaprilatın sağlamlığı değil, kaprilatın kullanıldığı bir inaktivasyon prosedürünün sağlamlığı söz konusu olsa gerek.
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4 KudoZ points awarded for this answer.
7 hrs

kaprilat dayanıklılık/direnç testi

İnternette aramalar herhangi bir sonuç vermiyor, fakat bu şekilde kullanılabilir diye düşünüyorum.
Peer comment(s):

neutral liz askew : but this = durability test? surely not the same thing as "robustness"?
1 hr
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Reference comments

2 hrs
Reference:

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no findings for your phrase

I suggest you get back to the client

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Note added at 8 horas (2023-10-25 21:20:35 GMT)
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only finding

https://pubmed.ncbi.nlm.nih.gov/12127317/

Compared to solvent-detergent treatment, BVDV inactivation in Fraction II+III solution was significantly faster (20-60 fold) using 16 mM caprylate. Caprylate-mediated inactivation of BVDV was not noticeably affected by temperature within the range chosen manufacturing the immunoglobulin product.

Our data show that caprylate is a robust enveloped virus inactivating agent for immunoglobulins and albumin which may potentially be utilized for other proteins; viral inactivation was not adversely affected by protein content and the buffer composition conditions evaluated. Within the parameters examined, caprylate inactivation of enveloped viruses provided comparable activity or advantages relative to the current, standard solvent-detergent treatment.

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Note added at 8 horas (2023-10-25 21:27:07 GMT)
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https://www.sciencedirect.com/science/article/abs/pii/S10451...

In the immunoglobin-rich solutions from Cohn Fraction II+III, human immunodeficiency virus, Type-1, bovine viral diarrhea virus (BVDV), and pseudorabies virus were inactivated by caprylate concentrations of ≥9 mM, ≥12 mM, and ≥9 mM, respectively. Compared to solvent-detergent treatment, BVDV inactivation in Fraction II+III solution was significantly faster (20–60 fold) using 16 mM caprylate. Caprylate-mediated inactivation of BVDV

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Note added at 8 horas (2023-10-25 21:37:36 GMT)
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Sağlamlık /Dayanıklılık (Robustness/ Ruggedness).

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Note added at 8 horas (2023-10-25 21:38:12 GMT)
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https://atauni.edu.tr/yuklemeler/481e00f25ce9621eede36124a66...

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Note added at 8 horas (2023-10-25 21:40:34 GMT)
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https://www.proz.com/kudoz/turkish-to-english/medical-pharma...

sağlamlık
Traducción al inglés: robustness
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