Glossary entry

English term or phrase:

immune confirmed progressive disease (“iCPD”) by iRECIST

Italian translation:

malattia progressiva immunologicamente confermata (= con metodiche/tecniche immunologiche) secondo i criteri iRECIST

Added to glossary by martini
Aug 16, 2023 13:37
9 mos ago
22 viewers *
English term

immune confirmed progressive disease (“iCPD”) by iRECIST

English to Italian Medical Medical: Pharmaceuticals
CONTESTO:

Screening and then at 12 weeks (±1 week) from treatment start (first exposure) and thereafter every 8 weeks ± 1 week until immune confirmed progressive disease (“iCPD”) by iRECIST, discontinuation of study drug(s), withdrawal of consent or loss to follow-up.


interpreto (e traduco) ...immune confirmed progressive disease (“iCPD”) by iRECIST... con "Malattia progressiva immunologicamente confermata (“iCPD”) secondo i criteri iRECIST"

attendo conferma (o smentita :) )

Grazie
Rino
References
see
Change log

Aug 21, 2023 15:22: martini Created KOG entry

Proposed translations

16 mins
Selected

malattia progressiva confermata dal sistema immunitario secondo i criteri iRECIST

ho trovato questo

iCPD: malattia progressiva confermata dal sistema immunitario

utilizzando i criteri di valutazione della risposta immunitaria nei criteri dei tumori solidi (iRECIST 1.1)

https://ichgcp.net/it/clinical-trials-registry/NCT03179410
Peer comment(s):

neutral EleoE : Confermata dal sistema immunitario???
5 hrs
Something went wrong...
3 KudoZ points awarded for this answer. Comment: "Concettualmente sono d'accordo. Allora utilizzerei ciò che ho presupposto nella mia domanda: "malattia progressiva immunologicamente confermata (= con metodiche/tecniche immunologiche) secondo i criteri iRECIST"."
+1
2 hrs

malattia progressiva confermata (iCPD) secondo i criteri iRECIST

..

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Note added at 2 heures (2023-08-16 16:34:38 GMT)
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imune is in the acronymn "iRECIST

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Note added at 2 heures (2023-08-16 16:34:56 GMT)
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see

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5648544/

“i” indicates immune responses assigned using iRECIST. RECIST=Response Evaluation Criteria in Solid Tumours. iUPD=unconfirmed progression. iCPD=confirmed progression. iCR=complete response. iPR=partial response. iSD=stable disease.
Note from asker:
....e "imune"?
Peer comment(s):

agree EleoE : iRECIST = response evaluation criteria in solid tumors modified for immune-based therapeutics.
3 hrs
Grazie!
Something went wrong...
7 hrs

malattia immun. progressiva confermata (iCPD) mediante criteri di risposta immunocorrelati (iRECIST)

immune confirmed progressive disease (iCPD) by iRECIST = malattia immunitaria progressiva confermata (iCPD) mediante criteri di risposta immunocorrelati (iRECIST)

iRECIST
A guideline for data management and data collection for trials testing immunotherapeutics

# MD, PhD
Canadian Cancer Trials Group, Kingston, Ontario
On behalf of the RECIST Working Group (RWG) and
Immunotherapy Subcommittee
... Guidelines for the evaluation of immune therapy activity in solid tumors: immune-related response criteria.
https://recist.eortc.org/recist/wp-content/uploads/sites/4/2...

I nuovi criteri di risposta immunocorrelati (iRECIST): sono sempre adeguati?
Fondazione IRCCS
Istituto Nazionale dei Tumori Milano
Criteri di risposta

- Gruppo di regole atte ad identificare il comportamento di una neoplasia durante un trattamento
- Linguaggio comune standardizzato per la misurazione della risposta dei tumori al trattamento
- Mirano a garantire l’obiettività ed a ridurre la variabilità tra osservatori
- Indispensabili per comparare risultati di studi differenti
Criteri radiologici di risposta
- Registrano le variazioni (principalmente dimensionali) di un tumore primario e delle sue lesioni secondarie al fine di valutare l’attività delle terapie antineoplastiche
https://www.aiom.it/wp-content/uploads/2019/02/20190524RM_22...


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Note added at 7 hrs (2023-08-16 21:04:07 GMT)
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1° link :
iRECIST
A guideline for data management and data collection for trials testing immunotherapeutics
Guidelines for the evaluation of immune therapy activity in solid tumors: immune-related response criteria.

iRECIST
A guideline for data management and data collection for trials testing immunotherapeutics

# MD, PhD
Canadian Cancer Trials Group, Kingston, Ontario
On behalf of the RECIST Working Group (RWG) and
Immunotherapy Subcommittee
... Guidelines for the evaluation of immune therapy activity in solid tumors: immune-related response criteria.
https://recist.eortc.org/recist/wp-content/uploads/sites/4/2...

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Note added at 7 hrs (2023-08-16 21:12:51 GMT)
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senza specificare

immune confirmed progressive disease (iCPD) by iRECIST = malattia immunitaria progressiva confermata (iCPD) da / mediante iRECIST
Something went wrong...

Reference comments

1 hr
Reference:

see

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5648544/

“i” indicates immune responses assigned using iRECIST. RECIST=Response Evaluation Criteria in Solid Tumours. iUPD=unconfirmed progression. iCPD=confirmed progression. iCR=complete response. iPR=partial response. iSD=stable disease.

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Note added at 1 heure (2023-08-16 15:30:13 GMT)
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iRECIST (immunotherapy RECIST)

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Note added at 1 heure (2023-08-16 15:36:31 GMT)
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Patterns of Response and Progression to Immunotherapy
ASCO Journals
https://ascopubs.org › doi › EDBK_200643
by E Borcoman · Cited by 220 — In March 2017, a consensus guideline named immunotherapy RECIST (iRECIST) was published after extensive work carried out by the RECIST working group along ...

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Note added at 2 heures (2023-08-16 15:46:42 GMT)
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CM082 più JS001 nel Carcinoma polmonare non a piccole cellule ...
https://ichgcp.net › NCT03848611
I soggetti identificati come **** malattia progressiva confermata (iCPD) secondo i criteri iRECIST**** devono interrompere il trattamento.
Something went wrong...
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