Jul 25, 2023 16:54
10 mos ago
24 viewers *
English term

payload

English to Polish Medical Medical: Pharmaceuticals
Z opisu nowego leku do stosowania w raku piersi

Consists of the same amino acid sequence as trastuzumab
Topoisomerase I inhibitor payload
Highly potent payload is an exatecan derivative, known as DXd, with a short systemic half-life
Upon release, membrane-permeable payload causes DNA damage and cell death, resulting in destruction of targeted tumor cells and surrounding cells, known as the bystander antitumor effect
Tumor-selective cleavable linker
Attaches payload to the antibody
Linker-payload is stable in plasma
Proposed translations (Polish)
3 +1 ładunek

Proposed translations

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34 mins
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Note added at 36 mins (2023-07-25 17:30:00 GMT)
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https://www.bankier.pl/static/att/emitent/2023-04/GK-CAPTOR-...

ADC łączą zdolność przeciwciał do bardzo specyficznego ukierunkowania na receptor lub. typ komórki z dołączoną toksyną, lub ładunkiem (ang. payload), ...


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Note added at 39 mins (2023-07-25 17:33:42 GMT)
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https://www.proteogenix.science/scientific-corner/adc/payloa...

Antibody-drug conjugates (ADCs) are an emerging class of pharmaceuticals designed to deliver highly toxic cargoes (payloads) to clinical targets. In ADCs, payloads are the pharmaceutically active component
Peer comment(s):

agree Crannmer : ładunek użyteczny
23 hrs
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