Each Versus Control (EVC) Design

English to German Medical Medical: Pharmaceuticals

Verschiedene Studien-Designs
8.11.3 Each Versus Control (EVC) Design—This design is applicable when three or more treatments are to be compared, and one of the treatments, symbolized by Tt, can be singled out as the control treatment. Carefully consider the choice of the control sample. It may be a different treatment, unfragranced base, treatment with water, or no treatment. The remaining treatments, T1, T2, ... Tt-1, are termed test treatments. Each subject receives the control treatment on one axilla and one of the t-1 test treatments on the other axilla. Each test treatment is randomly assigned to an approximately equal number of subjects. The assignment of treatments to the left and right axillae is random, but balanced so that each treatment appears the same number of times on the left as it appears on the right or as near to the same number of times as possible. A group of subjects all of whom receive the same pair of treatments (ignoring left/right assignment) is termed a cell. The EVC design has t-1 cells.