(time-point) time-course of effect

English to Polish Medical Medical: Pharmaceuticals clinical studies

"The primary analysis will compare the final time-point time-course of the treatment effect between the full-dose and placebo treatment groups".

Explanation: Pharmacokinetics gives us drug concentration versus time, while pharmacodynamics gives us drug effect versus concentration. Concentration is the link between drug dosing and effect. Linking pharmacokinetics and pharmacodynamics gives us drug effect versus time. This is called the time course of effect.