downstream processing

Portuguese translation: processamento a jusante

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00:55 Sep 23, 2020
English to Portuguese translations [PRO]
Science - Medical: Pharmaceuticals
Additional field(s): Biology (-tech,-chem,micro-), Medical: Pharmaceuticals, Medical (general)
English term or phrase: downstream processing
Definition from Pharma IQ:
Downstream Processing refers to the recovery and purification of biosynthetic products, particularly pharmaceuticals, from natural sources such as animal or plant tissue or fermentation broth, including the recycling of salvageable components and the proper treatment and disposal of waste. It is an essential step in the manufacture of pharmaceuticals such as antibiotics, hormones (e.g. insulin and human growth hormone), antibodies (e.g. infliximab and abciximab) and vaccines; antibodies and enzymes used in diagnostics; industrial enzymes; and natural fragrance and flavor compounds. Downstream processing is usually considered a specialized field in biochemical engineering.

Example sentence(s):
  • Downstream processing can also impact the distribution and levels of product-related impurities. Accurate monitoring of product-related impurities, including higher molecular weight and lower molecular weight species is critical for product safety. Science Direct
  • EasyMax chemical reactor is for fundamental parameter optimization in downstream processing method design and execution. METTLER TOLEDO
  • Furthermore, because chromatography can represent a significant portion of the cost of goods in downstream processing (DSP) operations, proper optimization of capacity and selectivity is required. BioPharm
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Question posted on behalf of translation team:
GBK medical and pharma specialistsGBK medical and pharma specialists


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Portuguese translation:processamento a jusante
Definition:
Processamento a jusante refere-se à recuperação e purificação de produtos biossintéticos, particularmente produtos farmacêuticos, a partir de fontes naturais, tais como tecidos de origem animal ou vegetal ou a fermentação de caldo.
Selected response from:

Fernando Barros
Brazil
Grading comment
4 KudoZ points were awarded for this answer



Summary of translations provided
5 +5processamento a jusante
Fernando Barros
5 +1Etapa de purificação (downstream) de um produto farmacêutico.
Paulo Moreira


  

Translations offered


2 hrs   confidence: Answerer confidence 5/5 peer agreement (net): +5
processamento a jusante


Definition from Wikimedia:
Processamento a jusante refere-se à recuperação e purificação de produtos biossintéticos, particularmente produtos farmacêuticos, a partir de fontes naturais, tais como tecidos de origem animal ou vegetal ou a fermentação de caldo.

Example sentence(s):
  • Após a etapa de bioprocesso de produção da enzima, há a necessidade de um processamento para a purificação e concentração da enzima. Esse processamento envolve um conjunto de operações unitárias e é denominado processo a jusante ou downstrean. - VerdArtis  
Fernando Barros
Brazil
Local time: 08:38
Native speaker of: Native in PortuguesePortuguese
PRO pts in category: 4

Votes in favor of/against selecting this as the best translation of the term asked
Yes  Silvia Tratnik
4 hrs

Yes  Kathleen Goldsmith-Killing
8 hrs

Yes  Jackeline Hentschel
17 hrs

Yes  Bruno Carminati
1 day 11 hrs

Yes  Alice Viana
64 days
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4 hrs   confidence: Answerer confidence 5/5 peer agreement (net): +1
Etapa de purificação (downstream) de um produto farmacêutico.


Definition from Anvisa:
O processamento downstream é um processo de purificação de um produto animal ou vegetal por meio de verificação de impurezas.

Example sentence(s):
  • Para o produto anteriormente inspecionado (Alfassebelipase), foi verificado apenas a parte de purificação (downstream), poi o IFA Alfassebelipase tem sua etapa de upstream na clara de ovo de galinhas transgências. - Anvisa  
Paulo Moreira
Brazil
Local time: 08:38
Native speaker of: Portuguese

Votes in favor of/against selecting this as the best translation of the term asked
Yes  Janisa Antoniazzi
2 hrs
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