磷酸化的介孔硅 (CMSN)

English translation: Phosphorylated CMSN or Phosphorylated Cationic Mesoporous Silica

GLOSSARY ENTRY (DERIVED FROM QUESTION BELOW)
Chinese term or phrase:磷酸化的介孔硅 (CMSN)
English translation:Phosphorylated CMSN or Phosphorylated Cationic Mesoporous Silica
Entered by: Rebekah Burdyshaw

15:58 Sep 16, 2016
Chinese to English translations [PRO]
Medical - Medical: Pharmaceuticals / Oncology, drug delivery nanoparticles
Chinese term or phrase: 磷酸化的介孔硅 (CMSN)
本研究利用Sialic acid(SA)对载体进行修饰以提高对TAM的靶向效率。首先构建了磷酸化的介孔硅(CMSN),经表面SA的修饰得到SA修饰的CMSN(SMSN).
Possible translation: "In this study, we used Sialic acid (SA) to modify carriers as a means to improve TAM targeting efficiency. We first constructed a core mesoporous nanoparticle (CMSN), and obtained SA-modified CMSN (SMSN) by modifying surface SA."

However, I am unsure, as I know that 磷酸化的 usually translates as "phosphorylated", and I also found possible definitions of CMSN as colloidal/chiral/core mesoporous silica nanoparticles. Your help is appreciated!
Rebekah Burdyshaw
United States
Local time: 12:36
Phosphorylated CMSN or Phosphorylated Cationic Mesoporous Silica
Explanation:
这里的“介孔硅”是简称,CMSN是特指,如果知道更多上下文,就知道具体指的是什么了。磷酸化的介孔硅就是phosphorylated CMSN。

介孔硅是Mesoporous Silica,而Mesoporous Silica Nanoparticles是指介孔硅纳米颗粒。由于这里谈到的是TAM(tumor-associated macrophages,肿瘤相关巨噬细胞)的靶向作用,所以CMSN有可能指阳离子介孔硅纳米颗粒Cationic Mesoporous Silica Nanoparticles,因为细胞表面特别是肿瘤细胞带负电荷,所以阳离子纳米粒容易被吸收。但也不能完全排除是Colloidal Mesoporous Silica Nanoparticles。

建议如果上下文未说明是哪种介孔硅,则可译为phosphorylated Mesoporous Silica Nanoparticles (CMSN) [sic], 或 phosphorylated Mesoporous Silica (CMSN) [sic],供参考。
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Sharon Tong
United States
Local time: 11:36
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Summary of answers provided
4Phosphorylated Colloidal Mesoporous Silica Nanoparticles (CMSNs)
Julia_Z
3core–shell/colloidal-shell mesoporous silica nanoparticles
Erzsébet Czopyk
3Phosphorylated CMSN or Phosphorylated Cationic Mesoporous Silica
Sharon Tong


  

Answers


23 mins   confidence: Answerer confidence 3/5Answerer confidence 3/5
core–shell/colloidal-shell mesoporous silica nanoparticles


Explanation:
Chiral mesoporous silica (CMS)
All-inorganic core–shell silica–titania mesoporous colloidal ...
xlink.rsc.org › Journals › Journal of Materials Ch... - Oldal lefordítása
Colloidal mesoporous silica (CMS) nanoparticles with a thin titania-enriched outer shell showing a spatially resolved functionality were synthesized by a delayed ...

Core–shell mesoporous silica nanoparticles improve HeLa cell growth ...
pubs.rsc.org › Journals › Journal of Materials Ch...
Herein, we report that a multiple core–shell functionalized colloidal mesoporous silica nanoparticle system (CMS) resulted in the electrostatic attraction of EGCG ...

Impact of different PEGylation patterns on the long-term bio-stability of ...
xlink.rsc.org › Journals › Journal of Materials Ch... - Oldal lefordítása
We describe colloidal-shell mesoporous silica (CMS) nanoparticles with an external coating of a hydrophilic polymer shell (poly(ethylene glycol), PEG).

Erzsébet Czopyk
Hungary
Local time: 17:36
Specializes in field
Native speaker of: Native in HungarianHungarian
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5 hrs   confidence: Answerer confidence 3/5Answerer confidence 3/5
Phosphorylated CMSN or Phosphorylated Cationic Mesoporous Silica


Explanation:
这里的“介孔硅”是简称,CMSN是特指,如果知道更多上下文,就知道具体指的是什么了。磷酸化的介孔硅就是phosphorylated CMSN。

介孔硅是Mesoporous Silica,而Mesoporous Silica Nanoparticles是指介孔硅纳米颗粒。由于这里谈到的是TAM(tumor-associated macrophages,肿瘤相关巨噬细胞)的靶向作用,所以CMSN有可能指阳离子介孔硅纳米颗粒Cationic Mesoporous Silica Nanoparticles,因为细胞表面特别是肿瘤细胞带负电荷,所以阳离子纳米粒容易被吸收。但也不能完全排除是Colloidal Mesoporous Silica Nanoparticles。

建议如果上下文未说明是哪种介孔硅,则可译为phosphorylated Mesoporous Silica Nanoparticles (CMSN) [sic], 或 phosphorylated Mesoporous Silica (CMSN) [sic],供参考。


Sharon Tong
United States
Local time: 11:36
Specializes in field
Native speaker of: Native in ChineseChinese
PRO pts in category: 4
Grading comment
Thank you!
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3 days 16 hrs   confidence: Answerer confidence 4/5Answerer confidence 4/5
Phosphorylated Colloidal Mesoporous Silica Nanoparticles (CMSNs)


Explanation:
As the background is not clear,
CMSN(s) may reffer to Colloidal Mesoporous Silica Nanoparticles
SMSN(s) may reffer to Spherical Mesoporous Silica Nanoparticles

磷酸化的介孔硅=
Phosphorylated CMSNs/Phosphorylated Colloidal Mesoporous Silica Nanoparticles (CMSNs)
or
Phosphorylation of Colloidal Mesoporous Silica Nanoparticles


Example sentence(s):
  • 本发明还提供了一种如上所述装载药物的纳米粒子的用途,所述装载药物的纳米粒子用作抗癌药物载体或细胞标记。本发明提供的介孔二氧化硅纳米粒子由于分散性好,具有丰富的纳米孔隙,并

    https://www.google.com/patents/CN104628007A?cl=zh
    Reference: http://slytt.com/4922649278/
Julia_Z
China
Local time: 00:36
Specializes in field
Native speaker of: Native in ChineseChinese
PRO pts in category: 4
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