Michael Beijer (asker) Oct 6, 2023:

thanks everyone! I have decided to go with:

minor plasma lipid =
in lage concentratie aanwezige plasmalipiden [in het Engels: minor plasma lipids]

the first time, and then just "in lage concentratie aanwezige plasmalipiden" after that

I've also asked my client and will report back if they have anything interesting to say!

Michiel Leeuwenburgh Oct 6, 2023:

Of "in lage concentratie aanwezige plasmalipiden" Of "in lage concentratie/laag gehalte voorkomende plasmalipiden" of een dergelijke constructie. Hiermee behoud je de term "plasmalipiden", die volgens mij wel belangrijk is.

Michael Beijer (asker) Oct 5, 2023:

Bedankt "lipiden met een (zeer) lage plasmaconcentratie" klinkt best goed/duidelijk!

Barend van Zadelhoff Oct 5, 2023:

minor plasma lipids - lipiden met een (zeer) lage plasmaconcentratie


In a further embodiment, said plasma comprises minor plasma lipids.
In a preferred embodiment of current invention, said minor plasma lipids are chosen from the group of palmitoyl ethanolamide (PEA), stearoyl ethanolamide (SEA), arachidonoyl ethanolamide (AEA).
It was found that the presence of this level of (phospho)lipids in the plasma provides coagulation activities. In an embodiment, the total concentration of minor plasma lipids in the mammalian plasma is between 5 and 50 nmol/l, more preferably between 6 and 30 nmol/l.
In a more preferred embodiment of the invention, said composition comprises PEA, SEA and AEA, wherein each lipid is present at a concentration of between 0.2 and 14 nmol/l. In a further embodiment, each minor plasma lipid is present at a concentration between 0.5 and 12 nmol/l, more preferably between 0.8 and 8.5 nmol/l.

https://patents.google.com/patent/WO2021005064A1/en

Michael Beijer (asker) Oct 5, 2023:

@Barend: Indeed, I think that's what it means.

Although I don't agree with Chat-GPT's suggested translation, its initial statement seems to make sense:

'In this context, "minor plasma lipids" refers to a specific subset of lipids present in plasma. The term "minor" indicates that these lipids are present in lower concentrations compared to other lipids.'

Barend van Zadelhoff Oct 5, 2023:

minor --> plasma lipids in small amounts ? Given: 5 and 50 nmol/l

In addition to diacyl glycerophosphocholine and sphingomyelin, human plasma also contains small amounts of other glycerophospholipids, which may have special metabolic function. The structure and origin of these minor plasma lipids has not been determined.

Molecular species of glycerophospholipids and sphingomyelins of human plasma: Comparison to red blood cells | SpringerLink

Michael Beijer (asker) Oct 5, 2023:

hmm found:

"Different minor abundance plasma lipids significantly influence thrombin generation in vitro and significant differences in such lipids are linked to risk for venous thrombosis. Some plasma sphingolipids including glucosylceramide, lyso-sulfatide and sphingosine have anticoagulant properties whereas, conversely, some plasma phospholipid derivatives, including certain lyso-phospholipids and ethanolamides, have procoagulant properties. [...]"

(https://pubmed.ncbi.nlm.nih.gov/29082360/ )

=>

minor plasma lipids = minor abundance plasma lipids?